Mabel™ Spherical Carbon for Cats

Akkermansia muciniphila is a bacterium that lives in the mucus layer lining your gut. That layer is the barrier between your digestive tract and the rest of your body, and Akkermansia is what maintains it. It feeds on the mucus and signals your gut to produce more, keeping the barrier thick.

When Akkermansia levels drop, the barrier thins. Lower levels have been linked to gut barrier dysfunction, bloating, and digestive symptoms. It's one of the most-researched strains in modern gut science.

It also works on the transporters that move uric acid out of you. In animal studies, ABCG2 — the protein that pushes urate out through both the kidney and the gut wall — increased, while the two that pull it back decreased.

Most Akkermansia supplements sell the live form. NOVO Health® uses pasteurized Akkermansia, the form proven in the 2019 Nature Medicine clinical trial to outperform live bacteria. Pasteurization stabilizes the active outer membrane protein (Amuc_1100) that interacts with your gut, and the pasteurized form survives stomach acid more reliably. We also disclose the exact strain (WB-STR-0001) and dose (100 million AFU per capsule). Most competitors hide this in proprietary blends.

No. Not a point, not half a point. That figure is set by your urate-lowering prescription. Nobody has measured what this organism does to serum urate in humans, and we will not claim it does anything.

You can, but it will not help once a flare has started. That is colchicine, an NSAID, or whatever your doctor has given you. NOVO works on clearance between flares, not on an attack in progress.

No. Nothing in the capsule breaks anything down. It works on the way out, not on the deposits.

No, and for gout this matters more than for most conditions. Untreated high uric acid damages joints and kidneys over time. If you are on allopurinol or febuxostat, stay on it. NOVO works on a different part of the problem — how much leaves — and it does not lower the number your prescription controls.

Akkermansia is well-tolerated in published research. The most common reported effects when starting any new gut supplement are mild and temporary. There can be slight changes in bowel movements or minor gas during the first few days as the gut adjusts. These typically resolve within a week. If you experience anything more significant, stop taking it and consult your doctor.

Most probiotics on the market are general-purpose strains (Lactobacillus, Bifidobacterium) that have shown mixed results in clinical research. Akkermansia muciniphila is a different category. It's a specific gut barrier bacterium with peer-reviewed human trial data showing improvements in metabolic markers. If you've tried general probiotic blends and felt nothing, that's not unusual. NOVO Health® uses the single strain with the strongest published evidence, in the pasteurized form that outperformed live in the trial.

For most common supplements; multivitamins, vitamin D, magnesium, fish oil, collagen, fiber, the answer is yes. Akkermansia is a single strain that works at your gut lining, so it doesn't compete with nutrients for absorption. Other live probiotics are fine alongside it too. Because NOVO's form is pasteurized, it isn't competing with those strains for colonization the way two live probiotics would. As always, if you're taking specific medical supplements under a doctor's care, run your full stack by them.

NOVO Health is manufactured in the United States in a facility that follows FDA Current Good Manufacturing Practices (cGMP) standards. Every batch is third-party tested for purity, potency, and microbial contamination before it's released. The Akkermansia strain itself (WB-STR-0001) is sourced from a documented commercial culture, not a generic bulk supplier. We disclose the strain on the label because most competitors don't. Strain transparency is how serious supplement brands signal what's actually in the bottle.

There is no clinical research on Akkermansia supplementation specifically during pregnancy or breastfeeding. While the bacterium is naturally present in the human gut, we recommend speaking with your doctor before starting any supplement during pregnancy or while nursing.

Store in a cool, dry place away from direct sunlight. Room temperature is fine. Pasteurized Akkermansia is shelf-stable and doesn't require refrigeration (unlike most live probiotics). Once opened, keep the bottle sealed between uses. Best used within the printed expiration date.